Cardinals at Rams

Prediction updated Tue, Oct 13 · 1:11 PM CT

Cardinals at Rams · Week 6 · Sun, Oct 18 · 3:05 PM CT · Fox

Our call: RamsStrong

5 of 5 models favor the Rams.

On average the models have the Rams by 9.9 points, a 79% win chance.

Updated until kickoff, then frozen.

Data through Week 5's games (the last played Mon, Oct 12), from nflverse play-by-play; nflverse last published it Tue, Oct 13 · 11:56 AM CT.

Arizona Cardinals (1–4) at Los Angeles Rams (2–3) Sun, Oct 18, 2026 Kickoff 3:05 PM CT on Fox Los Angeles

TV listings: ESPN

Weather: Indoors.

Every model

Model	Says	Win chance
Consensus (our call)The average of Our model, Elo, SRS and ESPN FPI (whichever are there); the market is left out. This is our call.	Rams by 9.9	79%
Our model ExperimentalOur ratings from nflverse play-by-play: opponent-adjusted EPA per play, home field and the starting quarterback, frozen on the 2024 season and tested once on 2025. Experimental.	Rams by 8.1	74%
EloEvery team's Elo rating from every game since 1999 (FiveThirtyEight's method).	Rams by 9.9	81%
SRSSimple Rating System: points scored minus allowed, adjusted for the schedule, blended with last season early on. Settings chosen by hand, not tuned.	Rams by 10.2	78%
ESPN FPIESPN's Football Power Index matchup predictor, read from ESPN before kickoff.	Rams by 11.3	86%
RecordThe team with the better record this season; equal records go to the home team. A winner only.	Rams	—
MarketThe market's margin, shown for comparison only: never a win chance, and not in our call.	Rams by 12.5	—

Our model is experimental. Season so far (79 games, Weeks 1–4 reconstructed): it missed the final margin by 9.8 points on average, the market's margin by 9.8; ours was closer in 38 of 79. Scorecard →

Numbers to know

All 5 models we track have the Rams.
Our call has had the winner in 4 of 5 Cardinals games and 2 of 5 Rams games this season (Weeks 1–4 reconstructed after the games).
The Cardinals have lost 4 straight.
Trey McBride is 3rd among tight ends with 308 receiving yards.
Michael Wilson needs 12 receiving yards for 300 this season (he averages 58 a game).
Matthew Stafford needs 1 touchdown pass for 10 this season (he averages 1.8 a game).
Jacoby Brissett needs 1 touchdown pass for 10 this season (he averages 1.8 a game).

Starting quarterbacks assumed

Cardinals: Jacoby Brissett (started the last game)
Rams: Matthew Stafford (started the last game)

Injuries

Injury statuses as of Tue, Oct 13, 6:05 PM CT.

The official injury report, as of Tue, Oct 13 · 9:57 AM CT: game status and practice status. Players with a game status or a missed or limited practice.

Cardinals

Week 5 report (last filed); Week 6 not filed yet.

Isaiah Adams G · Ankle · practice: Did not practiceOut
Andrew Wingard S · Knee · practice: Did not practiceOut
Walter Nolen DT · Calf · practice: LimitedQuestionable
Karson Sharar LB · Hamstring · practice: LimitedQuestionable

Rams

Week 5 report (last filed); Week 6 not filed yet.

Quentin Lake S · Hip · practice: LimitedQuestionable
Tyler Higbee TE · practice: Did not practice—
Alaric Jackson T · practice: Did not practice—
Aaron Donald DT · practice: Did not practice—
Byron Young LB · practice: Did not practice—
Grant Stuard LB · practice: Limited—
Josaiah Stewart LB · practice: Limited—

Full league injury report →

Latest news

Arizona Cardinals

Cardinals, Texans Complete Marvin Harrison Jr. Trade
OCTOBER 12, 3:22pm: In a statement announcing the trade, Cardinals general manager Monti Ossenfort said (via Josh Weinfuss of ESPN): “Decisions like this are never easy. Ultimately, we have to do what is best for our football team and that will always be the driving factor.

ProFootballRumors · Mon, Oct 12 · 3:22 PM CT · Read it at ProFootballRumors
Cardinals Place G Isaiah Adams On IR
After finding out they were losing left tackle Paris Johnson Jr. for the year earlier this week, the Cardinals now see starting right guard Isaiah Adams join him on injured reserve. Arizona reportedly doesn’t believe Adams’ ankle injury will keep him out as long as Johnson, but…

ProFootballRumors · Sat, Oct 10 · 3:22 PM CT · Read it at ProFootballRumors

More Cardinals news →

Los Angeles Rams

NFL Hands Rams LT Alaric Jackson Two-Game Suspension
Rams left tackle Alaric Jackson punched Bills outside linebacker Bradley Chubb after Buffalo defeated Los Angeles on Monday night. The NFL reviewed the incident and has decided to suspend Jackson two games without pay, Aaron Wilson of KPRC2 reports.

ProFootballRumors · Tue, Oct 13 · 3:51 PM CT · Read it at ProFootballRumors
Rams Cut K Harrison Mevis, Sign Blake Grupe
In the wake of a special teams meltdown in Week 5, the Rams are making a change at kicker. They are cutting Harrison Mevis and signing Blake Grupe off the Jets’ practice squad, according to Mike Garafolo and Ian Rapoport of NFL Network.

ProFootballRumors · Tue, Oct 13 · 12:27 PM CT · Read it at ProFootballRumors

More Rams news →

Headlines and a line or two from each outlet's own feed, linked to the original; the stories are theirs, not ours.

Matchup

Opponent-adjusted, from nflverse play-by-play, through the games before Week 6; league rank in brackets.

	Cardinals	Rams
Net EPA per play	−0.10 (27th)	+0.10 (4th)
Offense, EPA per play	0.00 (15th)	+0.05 (10th)
Defense, EPA per play allowed (lower is better)	+0.10 (29th)	−0.05 (3rd)
Passing offense, EPA per dropback	+0.03 (20th)	+0.11 (13th)
Rushing offense, EPA per run	−0.07 (16th)	−0.06 (15th)
Offense success rate	45% (11th)	46% (8th)

Last 5 meetings

The Rams won 4 of the last 5 meetings.

Jan 4, 2026Week 18, 2025	Rams 37, Cardinals 20at Los Angeles
Dec 7, 2025Week 14, 2025	Rams 45, Cardinals 17at Arizona
Dec 28, 2024Week 17, 2024	Rams 13, Cardinals 9at Los Angeles
Sep 15, 2024Week 2, 2024	Cardinals 41, Rams 10at Arizona
Nov 26, 2023Week 12, 2023	Rams 37, Cardinals 14at Arizona