The Sports Wire

Chargers at Bills

Prediction updated
Chargers at Bills · Week 3 · Sun, Sep 27 · 12:00 PM CT · Fox

Our call: BillsStrong

5 of 5 models favor the Bills.

On average the models have the Bills by 7.7 points, a 74% win chance.

Final: Bills 24, Chargers 16.

Closest: ESPN FPI (Bills by 8.2, missed by 0.2). 5 of 5 models named the winner.

Our call was right.

Reconstructed: Week 3 came before these pages existed, so every number here was worked out afterwards from data before the week, the same way as a live week (ESPN's FPI is the pre-game number ESPN still keeps). The scorecard keeps reconstructed weeks apart.

Data through Week 5's games (the last played Mon, Oct 12), from nflverse play-by-play; nflverse last published it .

Los Angeles Chargers (0–2) at Buffalo Bills (2–0) Sun, Sep 27, 2026 Kickoff 12:00 PM CT on Fox Buffalo

TV listings: ESPN

After the game

The Bills won 24–16. Allen threw for 204 yards. Our call (Bills, Strong) was right.

Leaders

Passing: completions-attempts, yards. Rushing: carries-yards. Receiving: catches-yards.

Team statsChargersBills
Yards gained348350
Passing yards217174
Rushing yards131176
Sacked2 (9 yards)4 (30 yards)
Interceptions thrown12

Los Angeles Chargers

Buffalo Bills

From nflverse's player stats, published the morning after the game: each team's numbers are its players' lines added up, and passing yards are net of the yards lost to sacks, as the NFL counts them.

Every model

ModelSaysWin chanceMissed by
Consensus (our call)The average of Our model, Elo, SRS and ESPN FPI (whichever are there); the market is left out. This is our call.Bills by 7.7 ✓74%0.3
Our model ExperimentalOur ratings from nflverse play-by-play: opponent-adjusted EPA per play, home field and the starting quarterback, frozen on the 2024 season and tested once on 2025. Experimental.Bills by 6.5 ✓69%1.5
EloEvery team's Elo rating from every game since 1999 (FiveThirtyEight's method).Bills by 9.3 ✓79%1.3
SRSSimple Rating System: points scored minus allowed, adjusted for the schedule, blended with last season early on. Settings chosen by hand, not tuned.Bills by 6.8 ✓69%1.2
ESPN FPI ClosestESPN's Football Power Index matchup predictor, read from ESPN before kickoff.Bills by 8.2 ✓78%0.2
RecordThe team with the better record this season; equal records go to the home team. A winner only.Bills ✓——
MarketThe market's margin, shown for comparison only: never a win chance, and not in our call.Bills by 7—1.0

Our model is experimental. Season so far (79 games, Weeks 1–4 reconstructed): it missed the final margin by 9.8 points on average, the market's margin by 9.8; ours was closer in 38 of 79. Scorecard →

Starting quarterbacks assumed

Injuries

The official Week 3 injury report as on file Mon, Oct 5 · 10:53 AM CT, saved after the fact like the rest of this reconstructed week: game status and practice status. Players with a game status or a missed or limited practice.

Chargers

  • Brenen Thompson WR · Quadricep · practice: Did not practiceOut
  • Charlie Kolar TE · Forearm · practice: Did not practiceOut
  • Trey Pipkins T · Knee · practice: Did not practiceOut
  • Kayode Awosika G · Fibula · practice: Did not practiceOut
  • Dalvin Tomlinson DT · Hamstring · practice: Did not practiceOut
  • Elijah Molden S · Hamstring · practice: Did not practiceOut
  • Trey Lance QB · Groin · practice: LimitedQuestionable
  • Rodney Shelley CB · Hamstring · practice: LimitedQuestionable

Bills

  • T.J. Sanders DE · Illness · practice: Did not practiceOut
  • Jordan Hancock CB · Hamstring · practice: Did not practiceOut
  • DJ Moore WR · Shoulder · practice: LimitedQuestionable
  • Keon Coleman WR · Ankle · practice: LimitedQuestionable
  • Ar'maj Reed-Adams G · Elbow · practice: LimitedQuestionable
  • Ed Oliver DT · Hip · practice: FullQuestionable
  • Terrel Bernard LB · practice: Did not practice—

Matchup

Opponent-adjusted, from nflverse play-by-play, through the games before Week 3; league rank in brackets.

ChargersBills
Net EPA per play−0.13 (31st)+0.08 (7th)
Offense, EPA per play−0.10 (30th)+0.16 (1st)
Defense, EPA per play allowed (lower is better)+0.04 (22nd)+0.08 (29th)
Passing offense, EPA per dropback0.00 (27th)+0.29 (2nd)
Rushing offense, EPA per run−0.24 (32nd)−0.04 (6th)
Offense success rate41% (26th)47% (4th)

Last 5 meetings

The Chargers won 3 of the last 5 meetings.

Dec 23, 2023Week 16, 2023Bills 24, Chargers 22at Los Angeles
Nov 29, 2020Week 12, 2020Bills 27, Chargers 17at Buffalo
Sep 16, 2018Week 2, 2018Chargers 31, Bills 20at Buffalo
Nov 19, 2017Week 11, 2017Chargers 54, Bills 24at Los Angeles
Sep 21, 2014Week 3, 2014Chargers 22, Bills 10at Buffalo