The Sports Wire

49ers at Rams

Prediction updated
49ers at Rams · Week 1 · Thu, Sep 10 · 7:35 PM CT · Netflix

Our call: RamsToss-up

5 of 5 models favor the Rams.

On average the models have the Rams by 2.2 points, a 57% win chance.

Final: 49ers 27, Rams 7.

Closest: Our model (Rams by 0.8, missed by 20.8). 0 of 5 models named the winner.

Our call was wrong.

Reconstructed: Week 1 came before these pages existed, so every number here was worked out afterwards from data before the week, the same way as a live week (ESPN's FPI is the pre-game number ESPN still keeps). The scorecard keeps reconstructed weeks apart.

Data through Week 5's games (the last played Mon, Oct 12), from nflverse play-by-play; nflverse last published it .

San Francisco 49ers (0–0) at Los Angeles Rams (0–0) Thu, Sep 10, 2026 Kickoff 7:35 PM CT on Netflix Melbourne Cricket Ground, Melbourne Neutral site

TV listings: ESPN

After the game

The 49ers won 27–7. Purdy threw for 205 yards and 3 touchdowns. Our call (Rams, Toss-up) was wrong.

Leaders

Passing: completions-attempts, yards. Rushing: carries-yards. Receiving: catches-yards.

Team stats49ersRams
Yards gained379290
Passing yards205168
Rushing yards174122
Sacked00
Interceptions thrown11

San Francisco 49ers

  • PassingBrock Purdy: 25 of 34 for 205 yards, 3 touchdowns, 1 interception
  • RushingChristian McCaffrey: 10 carries for 68 yards
  • ReceivingDemarcus Robinson: 2 catches for 50 yards, 1 touchdown
  • TacklesFred Warner: 11 tackles (5 solo)
  • SacksNo sacks

Los Angeles Rams

From nflverse's player stats, published the morning after the game: each team's numbers are its players' lines added up, and passing yards are net of the yards lost to sacks, as the NFL counts them.

Every model

ModelSaysWin chanceMissed by
Consensus (our call)The average of Our model, Elo, SRS and ESPN FPI (whichever are there); the market is left out. This is our call.Rams by 2.2 ✗57%22.2
Our model Experimental ClosestOur ratings from nflverse play-by-play: opponent-adjusted EPA per play, home field and the starting quarterback, frozen on the 2024 season and tested once on 2025. Experimental.Rams by 0.8 ✗53%20.8
EloEvery team's Elo rating from every game since 1999 (FiveThirtyEight's method).Rams by 2 ✗57%22.0
SRSSimple Rating System: points scored minus allowed, adjusted for the schedule, blended with last season early on. Settings chosen by hand, not tuned.Rams by 3 ✗59%23.0
ESPN FPIESPN's Football Power Index matchup predictor, read from ESPN before kickoff.Rams by 2.9 ✗60%22.9
RecordThe team with the better record this season; equal records go to the home team. A winner only.Rams ✗——
MarketThe market's margin, shown for comparison only: never a win chance, and not in our call.Rams by 3.5—23.5

Our model is experimental. Season so far (79 games, Weeks 1–4 reconstructed): it missed the final margin by 9.8 points on average, the market's margin by 9.8; ours was closer in 38 of 79. Scorecard →

Starting quarterbacks assumed

Injuries

The official Week 1 injury report as on file Mon, Oct 5 · 10:53 AM CT, saved after the fact like the rest of this reconstructed week: game status and practice status. Players with a game status or a missed or limited practice.

49ers

  • Alfred Collins DT · Knee · practice: Did not practiceOut
  • James Thompson Jr. DT · Hamstring · practice: LimitedQuestionable
  • George Kittle TE · practice: Limited—
  • Nick Bosa DE · practice: Limited—
  • Kyle Juszczyk FB · practice: Limited—

Rams

  • Aaron Donald DE · Not injury related - resting player · practice: Did not practiceOut

Last 5 meetings

The Rams won 4 of the last 5 meetings.

Nov 9, 2025Week 10, 2025Rams 42, 49ers 26at San Francisco
Oct 2, 2025Week 5, 202549ers 26, Rams 23at Los Angeles
Dec 12, 2024Week 15, 2024Rams 12, 49ers 6at San Francisco
Sep 22, 2024Week 3, 2024Rams 27, 49ers 24at Los Angeles
Jan 7, 2024Week 18, 2023Rams 21, 49ers 20at San Francisco