The Sports Wire

49ers at Chargers

Prediction updated
49ers at Chargers · Week 15 · Thu, Dec 17 · 7:15 PM CT · Prime Video

Our call: 49ersStrong

4 of 4 models favor the 49ers.

On average the models have the 49ers by 7.7 points, a 73% win chance.

Early prediction, updates weekly until kickoff.

Data through Week 5's games (the last played Mon, Oct 12), from nflverse play-by-play; nflverse last published it .

San Francisco 49ers (5–0) at Los Angeles Chargers (0–5) Thu, Dec 17, 2026 Kickoff 7:15 PM CT on Prime Video Los Angeles

TV listings: ESPN

Every model

ModelSaysWin chance
Consensus (our call)The average of Our model, Elo, SRS and ESPN FPI (whichever are there); the market is left out. This is our call.49ers by 7.773%
Our model ExperimentalOur ratings from nflverse play-by-play: opponent-adjusted EPA per play, home field and the starting quarterback, frozen on the 2024 season and tested once on 2025. Experimental.49ers by 7.271%
EloEvery team's Elo rating from every game since 1999 (FiveThirtyEight's method).49ers by 7.675%
SRSSimple Rating System: points scored minus allowed, adjusted for the schedule, blended with last season early on. Settings chosen by hand, not tuned.49ers by 8.373%
ESPN FPIESPN's Football Power Index matchup predictor, read from ESPN before kickoff. Read in the week of the game.Available game week—
RecordThe team with the better record this season; equal records go to the home team. A winner only.49ers—

Our model is experimental. Season so far (79 games, Weeks 1–4 reconstructed): it missed the final margin by 9.8 points on average, the market's margin by 9.8; ours was closer in 38 of 79. Scorecard →

Numbers to know

Starting quarterbacks

Not named yet. The quarterbacks we assume show here in game week: once every earlier game is in, or two days before Week 15's first kickoff.

Injuries

The official Week 15 injury report isn't out yet. It shows here once nflverse has it, in the week of the game.

Latest news

San Francisco 49ers

More 49ers news →

Los Angeles Chargers

More Chargers news →

Headlines and a line or two from each outlet's own feed, linked to the original; the stories are theirs, not ours.

Matchup

Opponent-adjusted, from nflverse play-by-play, through Week 5 (the games played so far); league rank in brackets.

49ersChargers
Net EPA per play+0.19 (1st)−0.10 (28th)
Offense, EPA per play+0.16 (2nd)−0.15 (32nd)
Defense, EPA per play allowed (lower is better)−0.03 (11th)−0.05 (8th)
Passing offense, EPA per dropback+0.31 (1st)−0.15 (32nd)
Rushing offense, EPA per run−0.05 (14th)−0.16 (26th)
Offense success rate51% (1st)40% (29th)

Last 5 meetings

The Chargers won 4 of the last 5 meetings.

Nov 13, 2022Week 10, 202249ers 22, Chargers 16at San Francisco
Sep 30, 2018Week 4, 2018Chargers 29, 49ers 27at Los Angeles
Dec 20, 2014Week 16, 2014Chargers 38, 49ers 35at San Francisco
Dec 16, 2010Week 15, 2010Chargers 34, 49ers 7at Los Angeles
Oct 15, 2006Week 6, 2006Chargers 48, 49ers 19at San Francisco